Worldwide, primary lung cancer remains the most common malignancy after non-melanocytic skin cancer. The World Health Organization (WHO) estimates lung cancer to be responsible for 1.59 million deaths globally per year, with smoking playing a major contributory role in 70% of cases.... Read more
Colorectal carcinomas arise from colorectal epithelium, which has undergone a series of molecular changes, referred to as the adenoma-carcinoma progression sequence. With increasing genetic mutations, progression from normal epithelium to adenomas with dysplasia occurs. Eventually, adenomas that show high-grade dysplasia give rise to invasive colorectal carcinomas.... Read more
All individuals with a positive family history of breast or ovarian cancer are not equally at risk. The likelihood that BRCA testing will be informative should be assessed prior to testing.... Read more
Electron microscopy (EM) is an essential component of diagnostic renal histopathology where it is used in conjunction with light microscopy and immunofluorescence studies.... Read more