AmpathChat #63 - Pharmacogenomics

Genetics

It is well established that unique patient characteristics exist to guide therapeutic drug decision making. These assist in optimising drug response and minimising adverse drug reactions (ADRs), and include age, weight, diet, co-morbidities, liver and renal function, as well as drug-drug interactions.... Read more

AmpathChat #48 - Expanded Chromosome Screening Of Products Of Conception (POCs)

Genetics

Ampath Genetics is excited to announce the introduction of products of conception (POCs) testing using next generation sequencing (NGS) technology. NGS allows analysis of all chromosomes (1-22, X and Y), resulting in significantly increased pick-up rates of chromosomal abnormalities when compared to conventional testing approaches.... Read more

AmpathChat #33 - Triple Negative Breast Cancer

Genetics

Breast cancer is the most common cancer among women worldwide, with approximately 1.7 million cases diagnosed annually. In South Africa, the incidence is 40 new cases per 100 000 persons per year. The incidence of breast cancer varies across the world between races and regions.... Read more

AmpathChat #10 - BRCA Gene Testing - A General Overview

Genetics

BRCA1 and BRCA2 gene testing is anything but straightforward. This article attempts to discuss the salient points to consider when faced with testing requests.... Read more

AmpathChat #73 - Familial Hypercholesterolaemia Detection Using NGS

Genetics

Familial hypercholesterolaemia (FH) is the most common autosomal-dominant inherited disorder of lipid metabolism.... Read more