Latest Ampath Alert

Lab Update 13 - First Trimester Pre-Eclampsia Screening

Nov 02, 2019 | Chemical Pathology

Pre-eclampsia (PE) is a major cause of maternal and neonatal morbidity and mortality, especially at early-onset (delivery at <34w gestation). Complications of PE include intracranial haemorrhage, HELLP syndrome, eclampsia, pulmonary oedema, renal failure, abruptio placentae, foetal growth restriction, intrauterine foetal death and preterm birth. Maternal future risks include cardiovascular, cerebrovascular or renal disease. Future risks to offspring born from affected pregnancies include hypertension, coronary artery disease and insulin resistance. In a South-African context, the prevalence of PE and severe PE is reported as 5.75% and 1.43% respectively. Global prevalence of PE varies between 2-5%....

Full Article