Immunology Articles



AmpathChat #55 - Tissue typing: HLA typing and screening

Ampath Immunology is proud to announce the introduction of HLA tissue typing and antibody screening using Luminex PCR-based multiplex technology.

AmpathChat #51 - Penicillin Allergy

Penicillin allergy is the most commonly reported antibiotic allergy. However, very few patients ever have their penicillin allergy confirmed. Furthermore, less than 20% of patients who report a positive history of a prior reaction to penicillin are found to be allergic to penicillin upon skin prick testing. Avoidance of penicillin based on self-reported allergic history alone often leads to the use of an alternate antibiotic with greater cost or side effect profile.

AmpathChat #38 - Diagnosing Primary immunodeficiencies (PID) - The Genetic Revolution

Primary immunodeficiencies (PID) are a diverse group of inborn errors in immunity. PID can present at any age, with the more severe forms presenting in infancy. Due to the heterogeneity of presentation and age of onset, the diagnosis of PID is often delayed or missed. There are at least 300 known genetic defects resulting in PID.

AmpathChat #31 - Screening for Inhalant Allergy In South Africa

Allergic rhinitis and inhalant allergy are common problems in primary care. Their diagnosis and subsequent management are often suboptimal. This may impact on a patient’s quality of life, asthma control and exacerbations

AmpathChat #12 - An Update on Autoimmune Limbic Encephalitis

Encephalitis (inflammation of the brain) is a pathological diagnosis, yet the diagnosis is made clinically. Diagnosis is made through the observation of neurologic dysfunction (e.g. depressed level of consciousness, seizures etc.) combined with corroborating findings of a cerebrospinal fluid (CSF) tap, EEG and neuroimaging studies.

AmpathChat #05 - Newborn Screening of Primary Immundeficiencies - TRECS and KRECS

Screening for severe primary immunodefi- ciencies involving the cellular and humoral immune system allows early detection and treatment, potentially saving the lives of babies affected by the disease.

AmpathChat #04 - Primary Immunodeficiencies - A Diagnostic Approach

Primary immunodeficiencies are a group of heterogenous genetic disorders that cause an enhanced susceptibility to recurrent and severe infections.

AmpathChat #03 - The Diagnostic Approach to Coeliac Disease

Coeliac disease used to be a disease of infancy, with children presenting with life-threatening malabsorbtion. Currently and more commonly, the disease presents between the ages of 10 and 40 with milder manifestations.

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